Detalhe da pesquisa
1.
Transmitted HIV-1 is more virulent in heterosexual individuals than men-who-have-sex-with-men.
PLoS Pathog
; 18(3): e1010319, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271687
2.
Modeling recapitulates the heterogeneous outcomes of SARS-CoV-2 infection and quantifies the differences in the innate immune and CD8 T-cell responses between patients experiencing mild and severe symptoms.
PLoS Pathog
; 18(6): e1010630, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35759522
3.
Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors.
J Theor Biol
; 572: 111568, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37393986
4.
Physical 'strength' of the multi-protein chain connecting immune cells: Does the weakest link limit antibody affinity maturation?: The weakest link in the multi-protein chain facilitating antigen acquisition by B cells in germinal centres limits antibody affinity maturation.
Bioessays
; 43(4): e2000159, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33448042
5.
A dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections.
Proc Natl Acad Sci U S A
; 116(35): 17393-17398, 2019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413198
6.
Interferon at the cellular, individual, and population level in hepatitis C virus infection: Its role in the interferon-free treatment era.
Immunol Rev
; 285(1): 55-71, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30129199
7.
Mutational pathway maps and founder effects define the within-host spectrum of hepatitis C virus mutants resistant to drugs.
PLoS Pathog
; 15(4): e1007701, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30934020
8.
Pre-existing resistance in the latent reservoir can compromise VRC01 therapy during chronic HIV-1 infection.
PLoS Comput Biol
; 16(11): e1008434, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33253162
9.
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection.
PLoS Comput Biol
; 16(12): e1008461, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33290397
10.
Early exposure to broadly neutralizing antibodies may trigger a dynamical switch from progressive disease to lasting control of SHIV infection.
PLoS Comput Biol
; 16(8): e1008064, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817614
11.
Concerted Interactions between Multiple gp41 Trimers and the Target Cell Lipidome May Be Required for HIV-1 Entry.
J Chem Inf Model
; 61(1): 444-454, 2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33373521
12.
Mechanistic insights into the effects of key mutations on SARS-CoV-2 RBD-ACE2 binding.
Phys Chem Chem Phys
; 23(46): 26451-26458, 2021 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34806722
13.
Trade-off between synergy and efficacy in combinations of HIV-1 latency-reversing agents.
PLoS Comput Biol
; 14(2): e1006004, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29451894
14.
Modelling how responsiveness to interferon improves interferon-free treatment of hepatitis C virus infection.
PLoS Comput Biol
; 14(7): e1006335, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30001324
15.
Strand-specific affinity of host factor hnRNP C1/C2 guides positive to negative-strand ratio in Coxsackievirus B3 infection.
RNA Biol
; 16(9): 1286-1299, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31234696
16.
Modeling how reversal of immune exhaustion elicits cure of chronic hepatitis C after the end of treatment with direct-acting antiviral agents.
Immunol Cell Biol
; 96(9): 969-980, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29744934
17.
Models of Viral Population Dynamics.
Curr Top Microbiol Immunol
; 392: 277-302, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26174625
18.
The two-component signalling networks of Mycobacterium tuberculosis display extensive cross-talk in vitro.
Biochem J
; 469(1): 121-34, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25929189
19.
Scaling law characterizing the dynamics of the transition of HIV-1 to error catastrophe.
Phys Biol
; 12(5): 054001, 2015 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26331636
20.
Inhibitors of hepatitis C virus entry may be potent ingredients of optimal drug combinations.
Proc Natl Acad Sci U S A
; 114(23): E4524-E4526, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512229